HELPING THE OTHERS REALIZE THE ADVANTAGES OF AHU'S

Close to 80% of TTP is induced by deficient action of ADAMTS13. ADAMTS13 deficiency may be constitutive, because of biallelic ADAMTS13 pathogenic variants; or acquired, due to an inhibitory antibody. Evaluation of ADAMTS13 activity is performed utilizing assessments dependant on the aptitude from the protease to cleave standard VWF multimers in vit